INFORMATION FOR BOTTLE FED BABIES ONLY. SMA Althéra® HMO should not be used unless prescribed by your healthcare professional.
Althéra® HMO
Whey based extensively hydrolyzed, nutritionally complete hypoallergenic speciality formula with 2 HMO (2’-FL and LNnT) and purified lactose for effective first-line symptom relief in cow’s milk protein allergy (CMPA).
- Proven hypoallergenicity with a tolerance of 98.4% in infants with cow’s milk protein allergy (CMPA) (Nowak-Wegryzn A, et al. Nutrients. 2019). Althéra HMO and Alfaré HMO have the highest degree of hydrolysis globally amongst extensively hydrolysed formulas (Nutten, 2021)
- Provides immune enhancing properties, with the addition of 2 HMO (2’-FL and LNnT†) and purified lactose to support the growth of beneficial bacteria and the production of important short chain fatty acids. (Vandenplas Y, et al. Nutrients. 202) )
- Reduces the risk of common respiratory-tract infections as well as medication use in infants with CMPA through the addition of 2’-FL and LNnT† to formula (Vandenplas Y, et al. Nutrients. 2022)
- Supports growth and development of infants and young children with CMPA (Vandenplas et al., Nutrients 2022) – commonly at risk of growth failure and nutritional deficiencies (Meyer et al., 2018; Christie et al., 2002)
- Inspired by breastmilk’s specific amino acid profile and with a protein quantity of 9 PE%
- Helps compliance with preferred taste over some casein based extensively hydrolysed formulas (Muraro et al., 2021)
†LNnT = Lacto-N-neotetraose; 2’-FL= 2’fucosyllactose; eHF = Extensively hydrolyzed formula; HMO = Human milk oligosaccharides; Docosahexaenoic acid (DHA); Arachidonic acid (ARA).
- 100% whey-based extensively hydrolyzed formula (eHF)
- Contains 2.2g protein /100kcal (9% energy from protein)
- Contains 5.7g purified lactose /100kcal (52% of added carbohydrate)
- Contains 2 Human Milk Oligosaccharides (HMO) - 2’-FL and LNnT†
- Contains DHA and ARA (1:1 ratio)
- Free from palm oil
Preparing Althéra® HMO is very similar to how you prepare standard infant formula. The step-by-step instructions on how to prepare Althéra® HMO are:
STEP 1 Wash hands before preparation.
STEP 2 Wash hands before preparation.
STEP 3 Boil for 5 min. Leave covered until use.
STEP 4 Boil drinking water for 5 min, allow to cool.
STEP 5 Pour exact amount of lukewarm water into bottle.
STEP 6 Pour exact amount of lukewarm water into bottle.
STEP 7 Shake bottle until powder fully dissolved.
STEP 8 Close tin tightly after each use and store in a cool, dry place.
WARNING “Unboiled water, unsterilsed bottles or incorrect dilution can make your baby ill. Incorrect storage, handling, preparation and feeding can also lead to adverse effects. Follow instructions carefully.”
| AGE | QTY PER MEAL (ML) | QTY PER MEAL (SCOOPS) | MEALS PER DAY |
|---|---|---|---|
|
1-2 weeks
|
90
|
3
|
6
|
|
3-4 weeks
|
120
|
4
|
7
|
|
2nd month
|
150
|
5
|
5
|
|
3-4 months
|
180
|
6
|
5
|
|
5-6 months
|
201
|
7
|
5
|
|
From 5th (7th) month**
|
210
|
7
|
3-5
|
Ingredients
lactose, maltodextrin, vegetable oils (suflower, rapeseed, coconut),extensively hydrolized whey protein (milk), minerals (calcium glycerophosphate, potassium phosphate, magnesium chloride, calcium chloride, sodium chloride, manganese sulfate, ferrous sulphate, potassium iodide, sodium phosphate, zinc sulphate, potassium citrate, potassium chloride, sodium selenate, copper sulphate), emulsifier (E472c), fibres (2'-fucosyllactose, lacto-N-neotetraose), mortierella alpina oil (ARA), oil from the micro-algae Schizochytrium sp.(DHA), acidity regulator (E330), choline bitartrate, vitamins (C, E, niacin, pantothenic acid, riboflavin, A, thiamin, B6, folic acid, K, D, biotin, B12), L-arginine, L-histidine, Taurine, Inositol, L-Carnitine.
For infants and young children with mild to moderate cow’s milk protein allergy (CMPA). It can be used as a sole source of nutrition from birth to 12 months of age, and as supplement in combination with age-appropriate complementary foods for infants from around 6 months of age.
Immune-nurturing benefits
CMPA is an immune-mediated disease. It is associated with gut microbiota dysbiosis, which impacts immune system maturation and leaves infants at an increased risk of infections and future allergies.8,25-33 Althéra® HMO contains lactose, as well as 2’-fucosyllactose (2’FL) and lacto-N-neotetraose (LNnT). 2’FL and LNnT are structurally identical to two significant human milk oligosaccharides (HMO).†8-13,34,35
Reducing infections and medication use
Infants fed formula with 2’FL and LNnT† had fewer upper and lower respiratory tract infections6,7,13
Infants fed formula with 2’FL and LNnT† had lower antibiotic and antipyretic use 6,7,13
Fictional case study for Althéra® HMO
NAME & AGE
Edward, 9 months old
FEEDING
Exclusively formula-fed
SYMPTOMS
Eczema, diarrhoea, inconsolable crying
DIAGNOSIS
Suspected CMPA
For the majority of infants with CMPA who cannot be breastfed, symptom relief can be achieved by eliminating cow’s milk proteins from the infant’s diet with an extensively hydrolysed formula,21-23 like Althéra® HMO.1-7
However, not all extensively hydrolysed formulas are the same. Althéra® HMO has the smallest peptide size (only 1% peptides above 1200 Daltons), resulting in a lower risk of allergic reactions.5
In an observational trial, an extensively hydrolysed formula with 10% peptides above 1200 Daltons did not achieve adequate allergy symptom control in >50% of infants, requiring amino acid formula reintroduction.5,40
Conversely, in a clinical trial, Althéra® was shown to relieve symptoms in 100% of infants with CMPA and is the only extensively hydrolysed formula to demonstrate similar efficacy and safety as an amino acid formula, which are generally reserved for severe symptoms of CMPA. Infants fed Althéra® also had:1
For the majority of infants with CMPA who cannot be breastfed, symptom relief can be achieved by eliminating cow’s milk proteins from the infant’s diet with an extensively hydrolysed formula,21-23 like Althéra® HMO.1-7
For the majority of infants with CMPA who cannot be breastfed, symptom relief can be achieved by eliminating cow’s milk proteins from the infant’s diet with an extensively hydrolysed formula,21-23 like Althéra® HMO.1-7
How it works
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IMPORTANT NOTICE: Mothers should be encouraged to continue breastfeeding even when their infants have CMA. This usually requires qualified dietary counselling to completely exclude all sources of cows’ milk protein from the mothers’ diet. If a decision to use a special formula intended for infants is taken, it is important to give instructions on correct preparation methods, emphasising that unboiled water, unsterilised bottles or incorrect dilution can all lead to illness. Formula for special medical purposes intended for infants must be used under medical supervision
