INFORMATION FOR BOTTLE FED BABIES ONLY. SMA Alfamino® Formula should not be used unless prescribed by your healthcare professional.
Alfamino® Formula
Amino acid-based, lactose free, nutritionally complete hypoallergenic specialty formula with 2 HMO (2’-FL and LNnT) and Medium Chain Triglycerides (MCT) for effective first-line symptom relief in infants and young children with severe forms of CMPA, MFPA or eHF failure.
- Proven hypoallergenicity in infants and children with CMPA (Nowak-Wegrzyn A, et al. Clin Pediatr. 2015)
- Provides immune enhancing properties, with the addition of 2 HMO (2’-FL and LNnT†) to support the growth of beneficial bacteria and the production of important short chain fatty acids. ( Gold MS, et al. Nutrients. 2022 (Alfamino))
- Supports growth and is well tolerated (Corkins M, et al. Pediatrics. 2016 ; Vandenplas Y, et al. Pediatr Gastroenterol Hepatol Nutr. 2021; Gold MS, et al. Nutrients. 2022) including in severe forms of CMPA (Cekola P, et al. Journal of Clinical Nutrition & Dietetics. 2021 ; Gold MS, et al. Nutrients. 2022)
- Facilitates fat absorption with lipid blend including the addition of 24.4% MCT (Łoś-Rycharska E, et al. Prz Gastroenterol. 2016; Høst A, 1999)
- with structured lipids (40% in sn-2 position) which has been associated with higher bone mineral density and better stool consistency (Kennedy K, et al. Am J Clin Nutr. 1999 ; Bongers M, et al., Journal Nutrition. 2007; Bach AC & Babayan VK. Am J Clin Nutr. 1982;Novak EM & Innis SM. Am J Physiol Endocrinol Metab. 2011)
- Helps compliance with preferred taste over some amino acid formulas (Muraro et al., 2021).
- 100% free amino acid-based formula (AAF)
- Contains 24.4% of fat as Medium Chain Triglycerides and structured lipids (40% in sn-2 position)
- Lactose free
- Contains 2 HMO - 2’-FL and LNnT†
- Contains DHA and ARA (1:1 ratio)
Preparing Althéra® HMO is very similar to how you prepare standard infant formula. The step-by-step instructions on how to prepare Althéra® HMO are:
STEP 1 Wash hands before preparation.
STEP 2 Wash hands before preparation.
STEP 3 Boil for 5 min. Leave covered until use.
STEP 4 Boil drinking water for 5 min, allow to cool.
STEP 5 Pour exact amount of lukewarm water into bottle.
WARNING “Unboiled water, unsterilsed bottles or incorrect dilution can make your baby ill. Incorrect storage, handling, preparation and feeding can also lead to adverse effects. Follow instructions carefully.”
AGE | QTY PER MEAL (ML) | QTY PER MEAL (SCOOPS) | MEALS PER DAY |
---|---|---|---|
1-2 weeks
|
90
|
3
|
6
|
Ingredients
Glucose syrup, vegetable oils (sunflower, rapeseed, structured palm oil), amino acids, MCT, starch, minerals (calcium glycerophosphate, potassium chloride, sodium citrate, calcium citrate, potassium citrate, sodium phosphate, magnesium oxide, ferrous sulphate, zinc sulphate, copper sulphate, potassium iodide, manganese sulphate, sodium selenate), emulsifier (E472c), Fibre(2'-Fucosyllactose, Lacto-N-Neotetraose), mortierella alpina oil (ARA), choline bitartrate, Schizochytrium sp. oil (DHA), vitamins (C, E, niacin, pantothenic acid, riboflavin, A, thiamin, B6, folic acid, K, D, biotin, B12), acidity regulator (E330), taurine, inositol, L-Carnitine.
For infants and young children with severe forms of cow’s milk protein allergy (CMPA), multiple-food protein allergy (MFPA), or those who fail on an eHF and for other conditions requiring an AAF (e.g., Eosinophilic Esophagitis, EoE). It can be used as a sole source of nutrition from birth to 12 months of age, and as a supplement in combination with age-appropriate complementary foods in infants from around 6 months of age.
Fictional case study for Althéra® HMO
NAME & AGE
Edward, 9 months old
FEEDING
Exclusively formula-fed
SYMPTOMS
Eczema, diarrhoea, inconsolable crying
DIAGNOSIS
Suspected CMPA
For the majority of infants with CMPA who cannot be breastfed, symptom relief can be achieved by eliminating cow’s milk proteins from the infant’s diet with an extensively hydrolysed formula,21-23 like Althéra® HMO.1-7
However, not all extensively hydrolysed formulas are the same. Althéra® HMO has the smallest peptide size (only 1% peptides above 1200 Daltons), resulting in a lower risk of allergic reactions.5
In an observational trial, an extensively hydrolysed formula with 10% peptides above 1200 Daltons did not achieve adequate allergy symptom control in >50% of infants, requiring amino acid formula reintroduction.5,40
Conversely, in a clinical trial, Althéra® was shown to relieve symptoms in 100% of infants with CMPA and is the only extensively hydrolysed formula to demonstrate similar efficacy and safety as an amino acid formula, which are generally reserved for severe symptoms of CMPA. Infants fed Althéra® also had:1
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IMPORTANT NOTICE: Mothers should be encouraged to continue breastfeeding even when their infants have CMA. This usually requires qualified dietary counselling to completely exclude all sources of cows’ milk protein from the mothers’ diet. If a decision to use a special formula intended for infants is taken, it is important to give instructions on correct preparation methods, emphasising that unboiled water, unsterilised bottles or incorrect dilution can all lead to illness. Formula for special medical purposes intended for infants must be used under medical supervision